P04.01 Characterization of microglia/macrophage phenotypes in glioma patient-derived xenograft mouse models
نویسندگان
چکیده
منابع مشابه
Use of patient-derived xenograft mouse models in cancer research and treatment
Background of patient-derived xenograft mouse models Since most advanced cancers are still incurable, basic, preclinical and clinical cancer research remains necessary for developing new therapeutic modalities. Many cancer cell lines have been developed, which have for a long time been available for use in basic and preclinical cancer research. However, those cell lines have the disadvantage th...
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Recent evidence suggests that patient derived xenograft (PDX) models can maintain certain pathological and molecular features of the original disease. However, these characterizations are limited to immunohistochemistry or by tissue microarray analysis. We conducted a high-throughput sequencing of primary colon tumor and PDX has not been reported yet. Fresh primary colon cancer tissues that ori...
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leading cause of cancer-related death of North American males.1 The disease is at present incurable once it has metastasized, and most deaths from this disease are due to metastases that are highly resistant to current conventional therapies. Prostate cancer is considered a multifocal disease that generally consists of a dominant cancer and one or more concurrent cancers of smaller volume with ...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2016
ISSN: 1523-5866,1522-8517
DOI: 10.1093/neuonc/now188.079